Hereditary sensory and autonomic neuropathy type IV and orthopaedic complications

SummaryHereditary sensory and autonomic neuropathy type IV (HSAN-IV) is a very rare autosomal recessive disorder characterized by recurrent episodes of unexplained fever, extensive anhidrosis, total insensitivity to pain, hypotonia, and mental retardation. The most frequent complications of this disease are corneal scarring, multiple fractures, joint deformities, osteomyelitis, and disabling self-mutilations. We reported the case of a 12-year-old boy. The goal was to discuss our decision-making and compare this case with cases described in the literature

Integration of Human Walking Gyroscopic Data Using Empirical Mode Decomposition

The present study was aimed at evaluating the Empirical Mode Decomposition (EMD) method to estimate the 3D orientation of the lower trunk during walking using the angular velocity signals generated by a wearable inertial measurement unit (IMU) and notably flawed by drift. The IMU was mounted on the lower trunk (L4-L5) with its active axes aligned with the relevant anatomical axes. The proposed method performs an offline analysis, but has the advantage of not requiring any parameter tuning. The method was validated in two groups of 15 subjects, one during overground walking, with 180° turns, and the other during treadmill walking, both for steady-state and transient speeds, using stereophotogrammetric data. Comparative analysis of the results showed that the IMU/EMD method is able to successfully detrend the integrated angular velocities and estimate lateral bending, flexion-extension as well as axial rotations of the lower trunk during walking with RMS errors of 1 deg for straight walking and lower than 2.5 deg for walking with turns

Idiopathic club foot treated with the Ponseti method. Clinical and sonographic evaluation of Achilles tendon tenotomy. A review of 221 club feet

SummaryThe Ponseti method applied to treating idiopathic club foot consists in placing successive corrective casts, possibly an Achilles tendon tenotomy, then derotation braces, a method that has proven its efficacy. This study compared 221 cases of club foot treated with this method between 2002 and 2007 divided into two groups, based on whether or not Achilles tendon tenotomy was performed. Assessment was both clinical and sonographic. We observed clear improvement of the results in the group that underwent Achilles tendon tenotomy and a significant difference in the rate of secondary surgery. The sonographic evaluation also showed improvement of the morphological results. We now systematically propose Achilles tendon tenotomy however severe club foot may be

Cosmic strings and Natural Inflation

In the present work we discuss cosmic strings in natural inflation. Our analysis is based entirely on the CMB quadrupole temperature anisotropy and on the existing upper bound on the cosmic string tension. Our results show that the allowed range for both parameters of the inflationary model is very different from the range obtained recently if cosmic strings are formed at the same time with inflation, while if strings are formed after inflation we find that the parameters of the inflationary model are similar to the ones obtained recently.Comment: 12 pages, 0 tables, 4 figures, accepted for publication in JHE

MASCOTTE: Model for AnalySing and foreCasting shOrT TErm developments

MASCOTTE is the new version of the Banque de France's macro-econometric forecasting model. Following the last rebasing of National Accounts (currently at 1995 price), the previous version of the model was simplified, re-specified and re-estimated. The model is essentially used for making macro-economic projections of the French economy over a two-to-three year horizon, which requires an accounting framework as close as possible to the French National Accounts. The main agents are companies, households, general government and the rest of the world. The new version now includes a supply block derived from the explicit optimisation behaviour of companies using a Cobb-Douglas technology under imperfect competition, and a new Wage Setting schedule. Full homogeneity of the nominal side of the model ensures the independence between the nominal equilibrium and the real equilibrium, the latter being only determined in the long run by relative prices. Furthermore, as regards the specification of equations, special attention was paid to the consequences of changes in short-term interest rates.Macro-economic model ; Applied econometrics ; Forecasting ; France

Estimation of the Centre of Mass from Motion Capture and Force Plate Recordings: A Study on the Elderly

The estimation of the centre of mass position in humans is usually based on biomechanical models developed from anthropometric tables. This method can potentially introduce errors in studies involving elderly people, since the ageing process is typically associated with a modification of the distribution of the body mass. In this paper, an alternative technique is proposed, and evaluated with an experimental study on 9 elderly volunteers. The technique is based on a virtual chain, identified from experimental data and locating the subject\u27s centre of mass. Its configuration defines the location of the centre of mass, and is a function of the anatomical joint angles measured on the subject. This method is a valuable investigation tool in the field of geronto-technology, since it overcomes some of the problems encountered with other CoM estimation methods

Small-Angle CMB Temperature Anisotropies Induced by Cosmic Strings

We use Nambu-Goto numerical simulations to compute the cosmic microwave background (CMB) temperature anisotropies induced at arcminute angular scales by a network of cosmic strings in a Friedmann-Lemaitre-Robertson-Walker (FLRW) expanding universe. We generate 84 statistically independent maps on a 7.2 degree field of view, which we use to derive basic statistical estimators such as the one-point distribution and two-point correlation functions. At high multipoles, the mean angular power spectrum of string-induced CMB temperature anisotropies can be described by a power law slowly decaying as \ell^{-p}, with p=0.889 (+0.001,-0.090) (including only systematic errors). Such a behavior suggests that a nonvanishing string contribution to the overall CMB anisotropies may become the dominant source of fluctuations at small angular scales. We therefore discuss how well the temperature gradient magnitude operator can trace strings in the context of a typical arcminute diffraction-limited experiment. Including both the thermal and nonlinear kinetic Sunyaev-Zel'dovich effects, the Ostriker-Vishniac effect, and the currently favored adiabatic primary anisotropies, we find that, on such a map, strings should be ``eye visible,'' with at least of order ten distinctive string features observable on a 7.2 degree gradient map, for tensions U down to GU \simeq 2 x 10^{-7} (in Planck units). This suggests that, with upcoming experiments such as the Atacama Cosmology Telescope (ACT), optimal non-Gaussian, string-devoted statistical estimators applied to small-angle CMB temperature or gradient maps may put stringent constraints on a possible cosmic string contribution to the CMB anisotropies.Comment: 17 pages, 9 figures. v2: matches published version, minor clarifications added, typo in Eq. (8) fixed, results unchange

Wavelet domain Bayesian denoising of string signal in the cosmic microwave background

An algorithm is proposed for denoising the signal induced by cosmic strings in the cosmic microwave background (CMB). A Bayesian approach is taken, based on modeling the string signal in the wavelet domain with generalized Gaussian distributions. Good performance of the algorithm is demonstrated by simulated experiments at arcminute resolution under noise conditions including primary and secondary CMB anisotropies, as well as instrumental noise.Comment: 16 pages, 11 figures. Version 2 matches version accepted for publication in MNRAS. Changes include substantial clarifications on our approach and a significant reduction of manuscript lengt